Patrick Mahomes passed for 262 yards and two touchdowns as two-time defending NFL champions Kansas City remained undefeated with a 27-20 victory over the reeling Las Vegas.

The Chiefs (7-0) extended their winning streak to 13 games, including the playoffs.

Their last loss was at home to Las Vegas, but the Chiefs are 5-0 against the Raiders at Allegiant Stadium and 6-0 there, including the Super Bowl in February.

Las Vegas (2-6) have lost four consecutive games, but this was the first time the Raiders had scored at least 20 points since a 20-16 victory over Cleveland on September 29.

Mahomes became the fastest quarterback in NFL history to reach 30,000 yards, doing it in his 103rd game. Matthew Stafford had hit that mark at 109 games.

Mahomes' top target was Travis Kelce, who had 10 catches for 90 yards, both season highs.

In Detroit, Jared Goff threw three touchdown passes and David Montgomery was the first of five players to score in the first half for the Detroit Lions, who romped past the Tennessee Titans 52-14.

The NFC North-leading Lions (6-1) have the conference's best record after winning five straight games, averaging 40-plus points over the past four.

Detroit had their highest-scoring game since a 55-point performance against Chicago in 1997.

The Titans (1-6) were routed for a second straight week.

In Cincinnati, Jalen Hurts rushed for three touchdowns and passed for another TD, helping the visiting Philadelphia pound the Bengals 37-17 for their third consecutive victory.

Hurts was 16-for-20 passing for 236 yards. He also had 10 carries for 37 yards.

Saquon Barkey rushed for 108 yards as Philadelphia (5-2) won for the fourth time in five games.

In Miami Gardens, Kyler Murray drove the Cardinals into position for a game-winning field goal by Chad Ryland as time expired for the second straight week, and Arizona spoiled Tua Tagovailoa's return from a concussion, beating the Dolphins 28-27.

Murray led two scoring drives in the fourth quarter to rally the Cardinals from a nine-point deficit. The first concluded with a two-yard touchdown run by James Conner that got Arizona (4-4) within 27-25. The second was a methodical 13-play, 71-yard march that ended with Ryland's 34-yard kick. A week earlier, Ryland was good from 32 yards on the final play to beat Los Angeles 17-15.

In Cleveland, Jameis Winston threw a 38-yard touchdown pass - his third of the game - to Cedric Tillman with 59 seconds left as the Browns stunned the visiting Baltimore Ravens 29-24 to snap a five-game losing streak.

Making his first start in two years and replacing injured starter Deshaun Watson, Winston helped the Browns (2-6) take down their AFC North rivals.

In Houston, the Texans beat the visiting Colts 23-20 to allow the home side to extend their lead atop the AFC South with a 6-2 record.

In other results, the Atlanta Falcons beat the Buccaneers 31-26, the LA Chargers thumped the visiting New Orleans Saints 26-8, and the Green Bay Packers pipped the Jacksonville Jaguars 30-27.

The Buffalo Bills scored an impressive 31-10 win on the road against the Seattle Seahawks, the Washington Commanders snuck past the Chicago Bears 18-15, and the New England Patriots beat the New York Jets 25-22.

In Denver, the Broncos beat the visiting Carolina Panthers 28-14, and in the late game the San Francisco 49ers scored a 30-24 victory over the Dallas Cowboys.